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Summaries of Review for Applications to RFA 08-01
The following is a listing of all applications reviewed under RFA 08-01 for CIRM New Faculty 2 Awards. Applications are ordered by application number and include the score (between 0 and 100, with 100 being the best) and a funding recommendation (indicated by the color key below) made by the Grants Working Group (GWG) during the review meeting on June 5-6, 2008. A link to the Public Abstract (provided by applicant), Statement of Benefit to California (provided by applicant), and Public Review Report are available for each application by clicking on the respective application number.
= Recommended for funding = Recommended if funds available = Not Recommended for funding
| Application Number | Title | Scientific Score |
|---|---|---|
| RN2-00900-1 | Prostate Cancer Stem Cells And Telomerase: Therapeutic Targeting And Clinical Significance | 63 |
| RN2-00902-1 | Stem Cells for Immune System Regeneration to Fight Cancer | 71 |
| RN2-00903-1 | Induction of cardiogenesis in pluripotent cells via chromatin remodeling factors | 76 |
| RN2-00904-1 | Stem Cells in Lung Cancer | 76 |
| RN2-00905-1 | Mechanisms of chromatin dynamics at enhancers during ES cell differentiation | 76 |
| RN2-00906-1 | Mechanisms of small RNA regulation in early embryonic development | 90 |
| RN2-00907-1 | Patient-specific pluripotent cell lines in Parkinson’s disease | -- |
| RN2-00908-1 | Regulation of Adult Stem Cell Proliferation by RAS and Cell-Permeable Proteins | 78 |
| RN2-00909-1 | VEGF signaling in adventitial stem cells in vascular physiology and disease | 67 |
| RN2-00910-1 | Derivation and Characterization of Myeloproliferative Disorder Stem Cells from Human ES Cells | 74 |
| RN2-00911-1 | Characterizing the Molecular Mechanisms of Pluripotent Stem Cell Self-Renewal | -- |
| RN2-00912-1 | Stem Cells and Induction of Lesion-Induced Neural Circuit Reorganization | -- |
| RN2-00913-1 | Redox Mechanisms of Human Neural Stem Cell Differentiation: Implications for Malignant Brain Tumor Treatment | -- |
| RN2-00914-1 | The Role of Stem Cells in Cartilage Repair and Regeneration | 65 |
| RN2-00915-1 | Mechanisms in Choroid Plexus Epithelial Development | 86 |
| RN2-00916-1 | Skeletogenic Neural Crest Cells in Embryonic Development and Adult Regeneration of the Jaw | 84 |
| RN2-00917-1 | Development of high-throughput screening platform for directing hESCs into pancreatic progenitor cells and mature pancreatic beta cells | -- |
| RN2-00918-1 | Craniosynostosis and the role of stem/progenitor cells in premature suture fusion and accelerated bone formation | 62 |
| RN2-00919-1 | High throughput modeling of human neurodegenerative diseases in embryonic stem cells | 89 |
| RN2-00920-1 | Biological Functions of Neural Stem Cells in the Adult Forebrain | -- |
| RN2-00921-1 | Building Cardiac Tissue from Stem Cells and Natural Matrices | 68 |
| RN2-00922-1 | Molecular mechanisms governing hESC and iPS cell self-renewal and pluripotency | 79 |
| RN2-00923-1 | The roles of non-coding RNAs in the self-renewal and differentiation of pluripotent stem cells | 81 |
| RN2-00924-1 | Embryonic Animal Model for Generation of Retinal/RPE Precursors from Human Stem Cells | -- |
| RN2-00925-1 | Epigenetic control of human embryonic stem cell (hESC) commitment and differentiation to skeletal muscles | -- |
| RN2-00926-1 | Effect of Microenvironment on Stem Cell Plasticity | -- |
| RN2-00927-1 | Therapeutic Regeneration of Skeletal and Smooth Muscles in Female Pelvic Floor Disorders with Human Muscle-Derived Stem Cells in Animal Models. | -- |
| RN2-00928-1 | Investigation of the Potential of Mouse Embryonic Stem Cells to Develop into Neuroendocrine Cells in Vitro | -- |
| RN2-00929-1 | Optimizing grafts for in utero transplantation through study of the changing potentials of hematopoietic stem cells in early ontogeny | -- |
| RN2-00930-1 | Targeting Cancer Stem Cells for Immunotherapy | -- |
| RN2-00931-1 | Molecular Mechanisms of Trophoblast Stem Cell Specification and Self-Renewal | 77 |
| RN2-00932-1 | Characterization of Placenta-Derived Stem Cells Using Raman Spectroscopy | -- |
| RN2-00933-1 | Laying the groundwork for building a tooth: analysis of dental epithelial stem cells | 82 |
| RN2-00934-1 | Mechanisms Underlying the Responses of Normal and Cancer Stem Cells to Environmental and Therapeutic Insults | 86 |
| RN2-00935-1 | Inducement, Characterization and Targeting of Human Cancer Stem Cells | -- |
| RN2-00936-1 | Epicardial progenitor cells in cardiac regeneration. | 65 |
| RN2-00937-1 | Mechanisms of neural stem cell self-renewal and differentiation in the brain and cancer | -- |
| RN2-00938-1 | Mechanisms Underlying the Diverse Functions of STAT3 in Embryonic Stem Cell Fate Regulation | 78 |
| RN2-00939-1 | Directed Stem Cell Recruitment into the CNS in Response to Coxsackievirus Infection | -- |
| RN2-00940-1 | The molecular basis underlying adult neurogenesis during regeneration and tissue renewal | 82 |
| RN2-00941-1 | Lung Cancer Initiating Cells (LCIC) from Malignant Pleural Effusion (MPE) and Dendritic Cells (DC) mediated immunotherapy strategies. | -- |
| RN2-00942-1 | Neural Progenitors and Alzheimer's Disease | -- |
| RN2-00943-1 | Hematopoietic differentiation of human pluripotent stem cells | 63 |
| RN2-00944-1 | Targeting mechanisms of stem cells for malignant brain tumors | -- |
| RN2-00945-1 | A Novel Microenvironment-Mediated Functional Skeletal Muscle from Human Embryonic Stem Cells and their In Vivo Engraftment | 76 |
| RN2-00946-1 | Mechanism of Tissue Engineered Small Intestine Formation | 71 |
| RN2-00947-1 | Toward Our Understanding of the Stem Cell Epigenome: Assessment of Epigenetic Alterations During Human Adult Adipose Derived Stromal Cells (ADSCs) Aging. | -- |
| RN2-00948-1 | Human placental stem cells | -- |
| RN2-00949-1 | Targeting bone homing of osteoprogenitors by high-affinity ligands to enhance bone regeneration | -- |
| RN2-00950-1 | Molecular dissection of adult liver regeneration to guide the generation of hepatocytes from pluripotent stem cells | 71 |
| RN2-00951-1 | Dopaminergic differentiation of hESCs: developing HTS for drug discovery and non-invasive tools for cell therapy strategy. | -- |
| RN2-00952-1 | Defining the Isoform-Specific Effects of Apolipoprotein E on the Development of iPS Cells into Functional Neurons in Vitro and in Vivo | 71 |
| RN2-00953-1 | Human Limbal Epithelial Stem Cell Conversion into Photoreceptors for Treatment of Retinal Degeneration | -- |
| RN2-00954-1 | Isolation of a homogeneous population of hESC-derived ventricular cardiomyocytes | -- |