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Summaries of Review for Applications to RFA 07-05
The following is a listing of all applications reviewed under RFA 07-05 for CIRM New Cell Lines Awards. Applications are ordered by application number and include the score (between 0 and 100, with 100 being the best) and a funding recommendation (indicated by the color key below) made by the Grants Working Group (GWG) during the review meeting on April 10-11, 2008. A link to the Public Abstract (provided by applicant), and Public Review Report are available for each application by clicking on the respective application number.
= Recommended for funding = Not Recommended for funding. Recommended to be available for funding only if the ICOC makes a programmatic determination to fund this application = Not Recommended for funding
| Application Number | Title | Scientific Score |
|---|---|---|
| RL1-00630-1 | Derivation of hESC Lines with Disease Lesions | 77 |
| RL1-00631-1 | Generating pluripotent cell lines from human neurons. | 59 |
| RL1-00632-1 | Induction of iPS Cells Using Transient Episomal Expression Vectors: Validation of Toxicity Testing in iPS-Derived Hepatocytes. | |
| RL1-00633-1 | High-fidelity derivation of new stem cell lines | 67 |
| RL1-00634-1 | Safe, efficient creation of human induced pluripotent stem cells without the use of retroviruses | 80 |
| RL1-00635-1 | Derivation of human embryonic stem cell lines from human blastocysts: analysis of genetic stability and ethnic diversity | 55 |
| RL1-00636-1 | Generation of Pluripotent Cell Lines from Human Embryos | 82 |
| RL1-00637-1 | Induced Pluripotent Stem Cell Lines from Retinal Pigment Epithelial Cells | 57 |
| RL1-00638-1 | Human Germ-Line Stem Cells As Source for Pluripotent Stem Cells | |
| RL1-00639-1 | Induced Pluripotent Stem Cells for Cardiovascular Diagnostics | 73 |
| RL1-00640-1 | Isolation and Characterization of A Novel Stem Cell Line from Amniotic Fluid and their Potential for Regenerative Medicine Applications | 56 |
| RL1-00641-1 | Generation and Testing of Induced Pluripotent Stem Cell Lines for Understanding Human Oligodendrocyte Development and Disease | |
| RL1-00642-1 | Derivation of New ICM-stage hESCs | 58 |
| RL1-00644-1 | Protein transduction of transcription factors: a non-genetic approach to generate new pluripotent cell lines from human skin. | 73 |
| RL1-00645-1 | Clinically Relevant iPS Cell Lines | |
| RL1-00646-1 | Derivation of hESC lines from multi-pronuclei zygotes | |
| RL1-00647-1 | Establishing Noonan and Leopard syndrome patient-specific iPS cell lines | 55 |
| RL1-00648-1 | Optimization of Human Embryonic Stem Cell Derivation Techniques and Production/Distribution of GMP-Grade Lines | 82 |
| RL1-00649-1 | Development of Induced Pluripotent Stem Cells for Modeling Human Disease | 69 |
| RL1-00650-1 | Establishment of Frontotemporal Dementia Patient-Specific Induced Pluripotent Stem (iPS) Cell Lines with Defined Genetic Mutations | 85 |
| RL1-00652-1 | GENERATION OF PLURIPOTENT STEM CELL LINES FROM SPERMATOGONIAL STEM CELLS APPLICABLE TO REGENERATIVE MEDICINE | |
| RL1-00653-1 | Derivation of New iPS Cell Lines and Development of a Novel Stem Cell Platform for Parkinson's Research and Therapeutic Applications | |
| RL1-00654-1 | Comparison of New Lines from Multiple Sources | |
| RL1-00655-1 | Large-Scale Reprogramming of Human Somatic Cells to a Pluripotent Stem Cell-Like State | |
| RL1-00656-1 | Generation of human ESC lines using SCNT | 57 |
| RL1-00657-1 | Creating the next generation of human iPS cells with global screens for and use of novel pluripotency factors | 56 |
| RL1-00658-1 | Placental Derived Stem Cells | |
| RL1-00659-1 | Establishment of Human Embryonic Stem Cells Modeling Human Disease by Somatic Cell Nuclear Transfer | |
| RL1-00660-1 | Induction of pluripotent stem cells by small RNA-guided transcriptional activation | 71 |
| RL1-00661-1 | Derivation of hES Cells in Novel Key Regulators of Cell Survival and Growth | |
| RL1-00662-1 | Derivation and analysis of pluripotent stem cell lines with inherited TGF-b mediated disorders from donated IVF embryos and reprogrammed adult skin fibroblasts | 79 |
| RL1-00663-1 | Creating stem cells for treatment of neurological disease: a novel microRNA-based method for safe, efficient induction of pluripotence in patient-specific cells | |
| RL1-00665-1 | Derivation of scalable clinical grade human embryonic stem cells under current Good Manufacturing Practice conditions using conventional and single blastomere biopsy protocols | 57 |
| RL1-00666-1 | Pluripotent human stem cells for creation of disease-specific and genotypically diverse 3-D liver tissues for drug discovery and patient therapies | |
| RL1-00667-1 | NEW TECHNOLOGY FOR THE DERIVATION OF HUMAN PLURIPOTENT STEM CELL LINES FOR CLINICAL USE | 85 |
| RL1-00668-1 | Derivation of Novel Late Onset Disease-Specific Stem Cell Lines Using Highly Accurate Single Cell Genotyping Technology | |
| RL1-00669-1 | Somatic cell age and memory in the generation of iPS cells | 78 |
| RL1-00670-1 | Derivation and comparative analysis of human pluripotent ESCs, iPSCs and SSCs: Convergence to an embryonic phenotype | 82 |
| RL1-00671-1 | Derivation of clinical grade HLA-homozygous human stem cell lines using parthenogenetic activation of oocytes | |
| RL1-00672-1 | In vitro and in vivo characterization of human neuronal precursor cells | |
| RL1-00674-1 | Derivation of new human pluripotent stem cells using small molecules | |
| RL1-00675-1 | Generation of human embryonic stem cell lines, under defined conditions, modeling normal & diseased states from material stored at the {REDACTED} embryo bank | 61 |
| RL1-00677-1 | Derivation of new induced pluripotent stem (iPS) cells to build neurological disease models | 63 |
| RL1-00678-1 | New Cell Lines for Huntington's Disease | 69 |
| RL1-00679-1 | Establishment of human embryonic stem cell lines using re-constructed human embryos derived from polyspermic eggs | |
| RL1-00680-1 | MicroRNA (miRNA)-induced Pluripotent Stem Cells (mirPS) | |
| RL1-00681-1 | Generation of clinical grade human iPS cells | 74 |
| RL1-00682-1 | Derivation of Parkinson's Disease Coded-Stem Cells (PD-SCs) | 67 |
| RL1-00683-1 | Generating Pluripotent Stem Cells from Skin of Patients with Multiple Sclerosis and Parkinson's Disease | |
| RL1-00684-1 | Generation of an Engineered Insulin Reporter hES Cell Line to Facilitate Cell-Based Assays for Diabetes Research |