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Summaries of Review for Applications to RFA 07-02
The following is a listing of all applications reviewed under RFA 07-02 for CIRM New Faculty Awards. Applications are ordered by application number and include the score (between 0 and 100, with 100 being the best) and a funding recommendation (indicated by the color key below) made by the Grants Working Group (GWG) during the review meeting on October 23-24, 2007. A link to the Public Abstract (provided by applicant), Statement of Benefit to California (provided by applicant), and Public Review Report are available for each application by clicking on the respective application number.
= Recommended for funding = Recommended if funds available = Not Recommended at this time
| Application Number | Title | Scientific Score |
|---|---|---|
| RN1-00525-1 | Skeletal muscle development from hESC and its in vivo applications in animal models of muscular dystrophy | 80 |
| RN1-00527-1 | Molecular mechanisms involved in adult neural stem cell maintenance | 90 |
| RN1-00528-1 | Characterization of Immune Responses in Human Embryonic Stem Cells | |
| RN1-00529-1 | Noncoding RNAs in Cell Fate Determination | 85 |
| RN1-00530-1 | Molecular mechanisms of neural stem cell differentiation in the developing brain | 77 |
| RN1-00531-1 | Inducing human embryonic stem cell differentiation into cardiomyocytes using extracellular matrix cues | |
| RN1-00532-1 | Identification of hESC-mediated molecular mechanism that positively regulates the regenerative capacity of post-natal tissues | 83 |
| RN1-00534-1 | Interactions Between Stem Cells and Cartilage in Health and Disease | |
| RN1-00535-1 | Bioengineering technology for fast optical control of differentiation and function in stem cells and stem cell progeny | 61 |
| RN1-00536-1 | Reprogramming of human somatic cells back to pluripotent embryonic stem cells | 65 |
| RN1-00537-1 | Investigation of the Potential of Mouse Embryonic Stem Cells to Develop into Neuroendocrine Cells in Vitro | -- |
| RN1-00538-1 | ES-Derived Cells for the Treatment of Alzheimer’s Disease | -- |
| RN1-00539-1 | Directed Stem Cell Recruitment into the CNS in Response to Coxsackievirus Infection | |
| RN1-00540-1 | Mechanisms of Stem Cell Fate Decisions | 65 |
| RN1-00541-1 | Induction of tolerance in NOD mice using genetically engineered human adipose-derived mesenchymal stem cells | |
| RN1-00542-1 | Role of Apolipoprotein E in Hippocampal Neurogenesis and Its Therapeutic Potential in Alzheimer’s Disease | |
| RN1-00544-1 | Characterization of mechanisms regulating de-differentiation and the re-acquisition of stem cell identity | 77 |
| RN1-00545-1 | Neural progenitors and Alzheimer’s disease | 58 |
| RN1-00546-1 | The role of hyaluronan in regulation of differentiation of hESCs in hematopoietic lineage | |
| RN1-00547-1 | Stem cell regeneration of neural circuits in murine Huntington’s disease models | |
| RN1-00549-1 | Epigenetic determinants of normal and tumor stem cell biology | 60 |
| RN1-00550-1 | Epigenetics in cancer stem cell initiation and clinical outcome prediction | 61 |
| RN1-00551-1 | Engraftment and Differentiation of Adult Human Stem Cells in Embryonic Eye | |
| RN1-00552-1 | Replenishing Dysfunctional Testes with Stem Cells | |
| RN1-00553-1 | Mechanisms of NANOG Function in hESC | 61 |
| RN1-00554-1 | Enhancing Survival of Embryonic Stem Cell-Derived Grafts by Induction of Immunological Tolerance | 59 |
| RN1-00555-1 | Building Cardiac Tissue from Stem Cells | |
| RN1-00557-1 | Mechanisms of Hematopoietic stem cell Specification and Self-Renewal | 73 |
| RN1-00558-1 | Using Stem Cells to Make, Study, and Sort Useful Forebrain Cells | |
| RN1-00559-1 | Isolation of Fetal Hepatic Stem Cells for In Utero Transplantation | |
| RN1-00560-1 | Identification and functional analysis of stem cells in acute lymphoblastic leukemia | |
| RN1-00561-1 | Combinatorial Chemistry Approaches to Develop LIgands against Leukemia Stem Cells | 94 |
| RN1-00562-1 | Transcriptional Regulation of Cardiac Pacemaker Cell Progenitors | 72 |
| RN1-00564-1 | In vitro reprogramming of mouse and human somatic cells to an embryonic state | 82 |
| RN1-00565-1 | Stem Cell Differentiation in Cytopenias | |
| RN1-00566-1 | A Novel Engineered Niche to Explore the Vasculogenic Potential of Embryonic Stem Cells | 90 |
| RN1-00568-1 | Designing a microenvironment niche for hepatic differentiation of hESCs | |
| RN1-00570-1 | Investigation of the molecular pathways that integrate self-renewal and cell structure in embryonic stem cells. | |
| RN1-00571-1 | A novel and generalizable organotypic slice model to evaluate stem cell potential for targeting pediatric brain tumors | |
| RN1-00572-1 | Oral and Craniofacial Reconstruction Using Mesenchymal Stem Cells | 69 |
| RN1-00573-1 | Immune Regulation of Retinal Stem Cell Migration and Survival | |
| RN1-00575-1 | Genetic dissection of mesodermal commitment to the hematopoietic fates. | 88 |
| RN1-00576-1 | A novel system for understanding the effects of natural genetic variation and epigenetics of stem cells. | |
| RN1-00577-1 | Genetic Encoding Novel Amino Acids in Embryonic Stem Cells for Molecular Understanding of Differentiation to Dopamine Neurons | 96 |
| RN1-00578-1 | Tumor Neovascularization by a Non-angiogenic Mechanism: Plasticity-based Contributions by Brain Stem Cells. | |
| RN1-00579-1 | Trithorax and Polycomb methyltransferase complexes in cell fate determination. | 92 |
| RN1-00583-1 | Developing a transplantation therapy for Parkinson’s disease using hESC-derived dopaminergic neurons. | |
| RN1-00584-1 | Generating pluripotent cell lines from neurons. | 90 |